VISDB Viral Integration Site DataBase

VIS ID

TVIS44020804

Fusion event

HTLV-1-HNRNPC integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr14

Cytoband

q11.2

Reference genome

Start

End

21733000/21264841 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-744-5p ; hsa-mir-455-3p ; hsa-mir-505-5p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-484 ; hsa-mir-342-3p ; hsa-mir-186-5p ; hsa-mir-30c-5p ; hsa-let-7e-5p ; hsa-mir-877-3p ; hsa-mir-485-3p ; hsa-mir-539-3p ; hsa-mir-136-3p ; hsa-mir-183-3p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-4533 ; hsa-mir-6775-5p ; hsa-mir-5090 ; hsa-mir-4517 ; hsa-mir-202-3p ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-548p ; hsa-mir-583 ; hsa-mir-1276 ; hsa-mir-4311 ; hsa-mir-548e-5p ; hsa-mir-224-5p ; hsa-mir-3924 ; hsa-mir-4539 ; hsa-mir-4724-5p ; hsa-mir-4511 ; hsa-mir-3133 ; hsa-mir-365b-5p ; hsa-mir-8052 ; hsa-mir-365a-5p ; hsa-mir-3199 ; hsa-mir-6503-3p ; hsa-mir-606 ; hsa-mir-708-5p ; hsa-mir-28-5p ; hsa-mir-3139 ; hsa-mir-4699-5p ; hsa-mir-4773 ; hsa-mir-7850-5p ; hsa-mir-620 ; hsa-mir-1270 ; hsa-mir-4531 ; hsa-mir-139-3p ; hsa-mir-4524a-3p ; hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-6828-3p ; hsa-mir-6071 ; hsa-mir-1298-5p ; hsa-mir-3157-5p ; hsa-mir-627-3p ; hsa-mir-6515-3p ; hsa-mir-1-5p ; hsa-mir-5000-5p ; hsa-mir-6781-3p ; hsa-mir-2682-3p ; hsa-mir-6877-3p ; hsa-mir-6819-3p ; hsa-mir-6731-5p ; hsa-mir-6783-5p ; hsa-mir-6824-5p ; hsa-mir-8085 ; hsa-mir-1323 ; hsa-mir-2053 ; hsa-mir-4432 ; hsa-mir-495-3p ; hsa-mir-499a-5p ; hsa-mir-5095 ; hsa-mir-548o-3p ; hsa-mir-555 ; hsa-mir-5688 ; hsa-mir-6504-3p ; hsa-mir-7-1-3p ; hsa-mir-7151-3p ; hsa-mir-7-2-3p ; hsa-mir-8087

Nearest miRNA

hsa-mir-6717/Upstream/241455; hsa-mir-1185-1/Downstream/1692109;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/160480, chr14-CpG: 50/Downstream/4406

Upstream sequence

TTTAAggccaagtgtggtggctcacacctgtaatcccaacactttgggaggccagggtagagcacggcttgagctcagtagtttgagaccagcctgggaa

Downstream sequence

acatgacgagactttattaaaaacaaaaaacattagcagggtgtggtagcctgaaatcccagctacttagcagtctgaggagcgaggatcacttgagccc