Basic Information
VIS ID
TVIS44020843
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
43616112/43146909 (Hg38)
End
43616112/43146909 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/6194518; hsa-mir-1185-1/Downstream/4614086;
Nearest TSS
ENST00000550708/Upstream/734336; ENST00000557465/Downstream/1237636;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/1539783, chr14-CpG: 22/Downstream/1740560
Nearby gene
LRFN5(+1242360) ;
Upstream sequence
ATAGAGAACACCAGCAAATGTACTCCTCTATTTCCTTTAAGTAAAATTTATTTTATCCTTTTTTATGATCCCATCATTCATTCCTTTAAACATTATGAAT
Downstream sequence
TCTTCATTGCATCCCTGGGTTATGAAAATTGTGGAGTTTTAGAAAATTGGATAACATCTCTTTACAGGTTATAAGATGGTGAAGAATCTTAAGGATTAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate