Basic Information
VIS ID
TVIS44020861
Fusion event
HTLV-1-LOC105370500 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
53267273/52800555 (Hg38)
End
53267273/52800555 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105370500
Nearest miRNA
hsa-mir-208a/Upstream/2500609; hsa-mir-1185-1/Downstream/1147872;
Nearest TSS
ENST00000550708/Upstream/8887; ENST00000556988/Downstream/19479;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/8654, chr14-CpG: 136/Downstream/149835
Nearby gene
GNPNAT1(-8887) ;
Upstream sequence
acttgaacccaggaggcagaggttgcagtgagctgagattgcaccactgcactacagcctgggcgatggagggagactctgtctaaaaaaaaaaaaaaaG
Downstream sequence
GTTTTTAGCATTAAAGAGCTGGTACTgccagacagtatgatttacacctgtaatcccagcactttgagagcctgaggtctcaagagtttgagaccagcct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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