VISDB Viral Integration Site DataBase

VIS ID

TVIS44020868

Fusion event

HTLV-1-NAA30 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr14

Cytoband

q22.3

Reference genome

Start

End

57860952/57394234 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-590-3p ; hsa-mir-130b-3p ; hsa-mir-93-5p ; hsa-mir-21-5p ; hsa-mir-15b-5p ; hsa-mir-183-5p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-mir-98-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-296-3p ; hsa-mir-569 ; hsa-mir-2053 ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-4802-5p ; hsa-mir-203a-3p ; hsa-mir-500a-3p ; hsa-mir-501-3p ; hsa-mir-502-3p ; hsa-mir-4666a-3p ; hsa-mir-6804-3p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-548c-3p ; hsa-mir-101-3p ; hsa-mir-144-3p ; hsa-mir-6510-3p ; hsa-mir-6888-3p ; hsa-mir-3120-5p ; hsa-mir-378g ; hsa-mir-4486 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3664-5p ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-1915-3p ; hsa-mir-2467-3p ; hsa-mir-377-5p ; hsa-mir-4257 ; hsa-mir-455-3p ; hsa-mir-486-3p ; hsa-mir-550b-2-5p ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-6764-5p ; hsa-mir-6798-5p ; hsa-mir-6805-5p ; hsa-mir-6807-5p

Nearest miRNA

hsa-mir-208a/Upstream/2516041; hsa-mir-1185-1/Downstream/2252728;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/2601, chr14-CpG: 124/Downstream/470724

Upstream sequence

ATGTGAGACACTTTCAGTTACTCTGTACttaaccattttatctttacctgttttcatagtaacattttcagttgttggtatctttttgaagttcttaaac

Downstream sequence

ttactctcagcaaatgtaacatagtacttccatttatttgttctaaatttaactttttggcttcctccagttttctatttgtagtgttctagaatttggG