Basic Information
VIS ID
TVIS44020871
Fusion event
HTLV-1-SYT16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
62334238/61867520 (Hg38)
End
62334238/61867520 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA14B
Target gene
SYT16
Nearest miRNA
hsa-mir-208a/Upstream/1218809; hsa-mir-1185-1/Downstream/2227504;
Nearest TSS
ENST00000550708/Upstream/2640; ENST00000430451/Downstream/128303;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/2597, chr14-CpG: 25/Downstream/189337
Nearby gene
SNAPC1(+71092) ;
Upstream sequence
gtttgtgagaattttgctagtttgtcttcagtgaatttcccctgtagccaacgtctagaagacccatatgctctgaactatgaattggaatctacataaa
Downstream sequence
agctacgagaattaataaatgagtctaacaagatgcaagggaaaatatacaaaaattgtttttctatatactagcaattaacttaaaacaatattattta
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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