Basic Information
VIS ID
TVIS44020874
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
65675538/65208820 (Hg38)
End
65675538/65208820 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA14B
Nearest miRNA
hsa-mir-208a/Upstream/164051; hsa-mir-1185-1/Downstream/126297;
Nearest TSS
ENST00000550708/Upstream/106125; ENST00000549235/Downstream/13527;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/105529, chr14-CpG: 46/Downstream/70791
Nearby gene
LINC02324(+4073) ;
Upstream sequence
AGGGTGGCTTCCTTGCTGGCCTCCCTGAGCGTCACAGAAGAAGCTGAGGACCAGAGTTCCCATTGGAAGGGGGGCAGTTGCCCAACTCAGGTTCAAGAAG
Downstream sequence
GATCCGTTAggccgggcgtggtggctcacgcctgtaatcccagcactgtggggggccgaggcaggcagatcacttgaggtcaggggtttgagaccagctt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate