Basic Information
VIS ID
TVIS44020876
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
65810215/65343497 (Hg38)
End
65810215/65343497 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA14B
Nearest miRNA
hsa-mir-208a/Upstream/8314; hsa-mir-1185-1/Downstream/127605;
Nearest TSS
ENST00000550708/Upstream/24707; ENST00000549235/Downstream/67095;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/63243, chr14-CpG: 191/Downstream/68271
Nearby gene
MIR4708(-8314) ;
Upstream sequence
aattcaatatgaatgtaataatttatcactcccttattaatgaacaattaaatagttgttagccaatttgcttttacaaacaatgctgtagctagcatcc
Downstream sequence
ttgtgcaggtcattttccatacatgcaactatatctgtaggataaatacctaaaactggaattgtcgggtcaagttcatttttggtttgaaagttattgc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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