Basic Information
VIS ID
TVIS44020882
Fusion event
HTLV-1-SLC10A1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
70248204/69781487 (Hg38)
End
70248204/69781487 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA14C
Target gene
SLC10A1
Nearest miRNA
hsa-mir-208a/Upstream/2339557; hsa-mir-1185-1/Downstream/2735333;
Nearest TSS
ENST00000550708/Upstream/10606; ENST00000555917/Downstream/15802;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/13536, chr14-CpG: 32/Downstream/68643
Upstream sequence
ttggctTACACATGAGATGACATGTCCACAGTCTACCCACAAAGGTGGCCCGCACAGGCTGGTGAGTGGTAGAAATAATCAGATTCTCTCATTTAGGAAG
Downstream sequence
TTTGCAGGATTACAGAGAGGGAAGCAATAGCAGGGACAAGTGTCAGAACAGAGGTCTGGGAGCAATAGCCACAAGTTGGCAGAAGTTGTAAGACAAAGGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate