Basic Information
VIS ID
TVIS44020886
Fusion event
HTLV-1-DPPA5P4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
75759025/75292322 (Hg38)
End
75759025/75292322 (Hg38)
Orient
+
Location type
Intronic
Target gene
DPPA5P4
Nearest miRNA
hsa-mir-208a/Upstream/812118; hsa-mir-1185-1/Downstream/1973896;
Nearest TSS
ENST00000550708/Upstream/12129; ENST00000561000/Downstream/2082;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/12227, chr14-CpG: 44/Downstream/1725
Nearby gene
LINC01220(No orient, 2082)
Upstream sequence
CTGGAGCATCCACTTGGTTTGGAGCTTGTACCAATAGGAGCTGTAAACCACGACCTCGGTGAGGTCTGAAGACTCCAGAGCCTTCAGCTGGAGCATGGCC
Downstream sequence
TTGCTCATCTGCTCGATGTAAGGGATTATCCATACGGGCCTGCTGGGGGAAGGGGATGAGAGCTCCCAGGTAGGGCACCCAGGCCAGCACTGGGCACACT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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