VISDB Viral Integration Site DataBase

VIS ID

TVIS44020893

Fusion event

HTLV-1-NRXN3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr14

Cytoband

q31.1

Reference genome

Start

End

80252406/79786063 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-374b-5p ; hsa-mir-92a-3p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-6880-5p ; hsa-mir-3165 ; hsa-mir-8071 ; hsa-mir-505-5p ; hsa-mir-4795-5p ; hsa-mir-192-3p ; hsa-mir-5189-3p ; hsa-mir-4786-5p ; hsa-mir-1915-5p ; hsa-mir-3667-3p ; hsa-mir-6849-3p ; hsa-mir-665 ; hsa-mir-1304-5p ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-3664-3p ; hsa-mir-1282 ; hsa-mir-5707 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-4478 ; hsa-mir-3929 ; hsa-mir-4419b ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-4695-5p ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-5690 ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-1227-3p ; hsa-mir-1273a ; hsa-mir-4252 ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-1273g-3p ; hsa-mir-3940-3p ; hsa-mir-508-5p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-6807-5p ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-4257 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p

Nearest miRNA

hsa-mir-1260a/Upstream/2519773; hsa-mir-1185-1/Downstream/14162163;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/506517, chr14-CpG: 23/Downstream/75608

Upstream sequence

tcacctgtgttcctgcagcaagacacacctctgtccccaccatgaggcagaatgaggcttgggacagataagacttccagaacccagctccagcactgtg

Downstream sequence

gccactgtctgattaatcagttcttcttctgcactgataattaaataCTCACTGTTAAATTTTATATTACCCTTGCTAGTATCATTGTTATAACCAATGT