Basic Information
VIS ID
TVIS44020894
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
80535490/80069147 (Hg38)
End
80535490/80069147 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1260a/Upstream/2802857; hsa-mir-1185-1/Downstream/13879079;
Nearest TSS
ENST00000550708/Upstream/94978; ENST00000553979/Downstream/142167;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/207159, chr14-CpG: 29/Downstream/872219
Nearby gene
DIO2(-128378) ;
Upstream sequence
AACCCAGTCAACCAGCAAATGCTTATCGAGAAATGAGTCTTGTTTTTGCATGCTACTGAGATGTTGTGGTTGTTATGCAACAGCTTGTCAGCAAATAACT
Downstream sequence
GACTGAAACAAGTGACAAGTAAGCAAATAACACTAATACATTGTTGTCAGTGATTTTATAAAAGACATTCTGGGTGCTAAAAAACAGAGACAAAGCAGAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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