Basic Information
VIS ID
TVIS44020922
Fusion event
HTLV-1-chr15 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
24391048/24145901 (Hg38)
End
24391048/24145901 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105370732 ; LOC105370733
Nearest miRNA
hsa-mir-1268a/Upstream/583770; hsa-mir-10393/Downstream/1702846;
Nearest TSS
ENST00000557528/Upstream/170729; ENST00000568541/Downstream/23956;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/267616, chr15-CpG: 29/Downstream/281136
Nearby gene
PWRN2(-18878) ;
Upstream sequence
aggagcaactagagacagacatagtattgcaccatttggctgaagtctttatgggtgtATTTGTCAGTTGTTTTTTttttccagagagacagggaggtag
Downstream sequence
ataggtaggtagatagatacatatatagatggagagttgatagatagataatagttcaatgagcggcattttgtttggggatttactcatgtaacattgt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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