Basic Information
VIS ID
TVIS44020925
Fusion event
HTLV-1-ATP10A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q12
Reference genome
GRCh37/hg19
Start
26107158/25862011 (Hg38)
End
26107158/25862011 (Hg38)
Orient
+
Location type
Intronic
Target gene
ATP10A
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1268a/Upstream/13186; hsa-mir-10393/Downstream/2564480;
Nearest TSS
ENST00000557528/Upstream/167186; ENST00000557558/Downstream/173;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/125766, chr15-CpG: 142/Downstream/345
Upstream sequence
CGGAGACTCTAAAACTCAGGGAGGGAAAAAGAGCAGGAGTGGTCCATCGCAGGGTCACCCCTGGTACTGCCCGTGGCAGGGCTCACAAACACCCCACAGC
Downstream sequence
CTCTTTCCCCCAGGAAGCAGGTTAAGATGAAGAAAATTAGGCAGGCAGCTACCGGGCGGTGCCTGGCTCGCGGCTCATGGCTCACAGTGGAGGATGGACA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate