Basic Information
VIS ID
TVIS44020943
Fusion event
HTLV-1-chr15 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q14
Reference genome
GRCh37/hg19
Start
39722549/39430348 (Hg38)
End
39722549/39430348 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1233-1/Upstream/2457447; hsa-mir-10393/Downstream/2261237;
Nearest TSS
ENST00000557528/Upstream/3153; ENST00000558846/Downstream/42355;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/864891, chr15-CpG: 109/Downstream/149978
Nearby gene
THBS1(+150731) ;
Nearest cancer related gene
THBS1(TSG, +150731) ;
Upstream sequence
AACACTGTGGGGGGAAGACTGAGGACAGAGGAAATGGAGAAAATGGGGGGAGCTAGGAATTTGTTGATAGCATATAAAAGTGGGCAACTGAAAGCACTGT
Downstream sequence
GAACTCTCTTTGTTTGAAAAGTGTAAGGGGACTAGTTTGTAGTATCCCTAAAAAGGTTTGCAGATCAAGAGTGGAACTGGGTTTCAAAGgccccagggcc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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