Basic Information
VIS ID
TVIS44020945
Fusion event
HTLV-1-OIP5-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q15.1
Reference genome
GRCh37/hg19
Start
41601343/41309145 (Hg38)
End
41601343/41309145 (Hg38)
Orient
+
Location type
Intronic
Target gene
OIP5-AS1
Nearest miRNA
hsa-mir-1233-1/Upstream/4336244; hsa-mir-10393/Downstream/382440;
Nearest TSS
ENST00000557528/Upstream/52235; ENST00000559659/Downstream/23342;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/24807, chr15-CpG: 82/Downstream/23019
Nearby gene
OIP5(-123) ;
Upstream sequence
agattataaattctaaggatagtgtgtctatttttgcttaccttttatccccagcacctagtctaacactttacaaatatatattaaattaatATTTTGA
Downstream sequence
TAAGTTACTCAAAGTGCTACATAAAACAAAATTATAGAAAATAGTACTTTGGTAACTGTTTCGTTTTATCATTGCTTTCATTATTTCTCTGTTAACCTCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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