VISDB Viral Integration Site DataBase

VIS ID

TVIS44020946

Fusion event

HTLV-1-TYRO3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr15

Cytoband

q15.1

Reference genome

Start

End

41864041/41571843 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-4455 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-6872-3p ; hsa-mir-518e-3p ; hsa-mir-518f-3p ; hsa-mir-518d-3p ; hsa-mir-518c-3p ; hsa-mir-518b ; hsa-mir-518a-3p ; hsa-mir-5096 ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-197-3p ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-4635 ; hsa-mir-3663-5p ; hsa-mir-4732-3p ; hsa-mir-4716-5p ; hsa-mir-4781-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-5580-5p ; hsa-mir-149-5p ; hsa-mir-3667-3p ; hsa-mir-877-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-3065-3p ; hsa-mir-6871-3p ; hsa-mir-1228-3p ; hsa-mir-1273e ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-203b-3p ; hsa-mir-2467-3p ; hsa-mir-25-5p ; hsa-mir-3612 ; hsa-mir-377-5p ; hsa-mir-4257 ; hsa-mir-4459 ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4695-5p ; hsa-mir-6086 ; hsa-mir-6087 ; hsa-mir-6499-3p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6516-5p ; hsa-mir-658 ; hsa-mir-665 ; hsa-mir-6761-5p ; hsa-mir-6840-3p ; hsa-mir-7158-3p ; hsa-mir-1273h-5p ; hsa-mir-1288-5p ; hsa-mir-149-3p ; hsa-mir-30b-3p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3122 ; hsa-mir-3197 ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-3913-5p ; hsa-mir-3929 ; hsa-mir-4419b ; hsa-mir-4433a-3p ; hsa-mir-4478 ; hsa-mir-450a-1-3p ; hsa-mir-4649-3p ; hsa-mir-4683 ; hsa-mir-4728-5p ; hsa-mir-4786-5p ; hsa-mir-485-5p ; hsa-mir-6502-3p ; hsa-mir-6513-5p ; hsa-mir-6765-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6788-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6884-5p ; hsa-mir-6888-5p ; hsa-mir-7106-5p ; hsa-mir-7112-5p ; hsa-mir-7160-5p ; hsa-mir-887-5p

Nearest miRNA

hsa-mir-1233-1/Upstream/4598942; hsa-mir-10393/Downstream/119742;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/12071, chr15-CpG: 61/Downstream/13400

Upstream sequence

AATATGAGATGGCAGCCTATAGGAGAGACTTTTGGACTCATCTGGTAAATAAATAGATGGCAAAATAGCAAGGAGGGTCCTGGCAGAAATCTGAGGTGAG

Downstream sequence

GAGTGCCAAAGGTCTGCACATGAAGACTGTGTggctggatgtggtggctcatgcctataacctcagcactttgggaggctgaggtgggagaattgcttga