Basic Information
VIS ID
TVIS44020970
Fusion event
HTLV-1-LINC01169 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q22.31
Reference genome
GRCh37/hg19
Start
66927183/66634845 (Hg38)
End
66927183/66634845 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA15A
Target gene
LINC01169
Nearest miRNA
hsa-mir-10393/Upstream/137811; hsa-mir-11181/Downstream/2167005;
Nearest TSS
ENST00000557528/Upstream/52655; ENST00000612349/Downstream/67383;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/12299, chr15-CpG: 26/Downstream/19964
Upstream sequence
CTTGAATTCCCTACCCGGTAGGGTGCACACCGGCACAGACTCTTCTGCCGCTGCTGGTGTGCAAATGCTGGTGGTATGGCCTCCCTTCTCCTCTATGGGC
Downstream sequence
ACTCATCCCCacagggtcatcaggtagggcctcactgaggaggtgTTGCTGTGCTGGCCAGGGAGGGGTCTCACCATGTCACAGGGAGGCTGTTTATTAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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