VISDB Viral Integration Site DataBase

VIS ID

TVIS44020993

Fusion event

HTLV-1-AP3S2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr15

Cytoband

q26.1

Reference genome

Start

End

90402320/89859088 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-19b-3p ; hsa-mir-18a-5p ; hsa-mir-20a-5p ; hsa-mir-6807-5p ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-769-5p ; hsa-mir-6751-3p ; hsa-mir-1199-5p ; hsa-mir-766-3p ; hsa-mir-6849-3p ; hsa-mir-4302 ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-4293 ; hsa-mir-449b-3p ; hsa-mir-508-5p ; hsa-mir-19a-3p ; hsa-mir-6862-5p ; hsa-mir-4253 ; hsa-mir-3945 ; hsa-mir-6774-5p ; hsa-mir-635 ; hsa-mir-4716-5p ; hsa-mir-3607-5p ; hsa-mir-4735-3p ; hsa-mir-18b-5p ; hsa-mir-548m ; hsa-mir-4786-5p ; hsa-mir-1247-3p ; hsa-mir-140-3p ; hsa-mir-2467-3p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-377-5p ; hsa-mir-4257 ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-500a-3p ; hsa-mir-5186 ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-6828-5p ; hsa-mir-767-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-1273e

Nearest miRNA

hsa-mir-10393/Upstream/8367; hsa-mir-1302-10/Downstream/24843;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/43747, chr15-CpG: 52/Downstream/34705

Upstream sequence

CTGGAACAATCCTTGcttttgtttttttctttttttttttcttttttacttaaagagatggggtctcacttattgctcaggctgttctcaaactcctggg

Downstream sequence

ctcaagtgatcctctcgcctcagcctcccaaagtgctggggattatcgtcgtgagcctccacaaccagccCAAGTGtccttccttccttcctttcttcct