Basic Information
VIS ID
TVIS44020999
Fusion event
HTLV-1-LINC02253 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q26.2
Reference genome
GRCh37/hg19
Start
97869901/97326671 (Hg38)
End
97869901/97326671 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC02253
Nearest miRNA
hsa-mir-10393/Upstream/993364; hsa-mir-1302-10/Downstream/1457755;
Nearest TSS
ENST00000557528/Upstream/7383; ENST00000559321/Downstream/84584;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/909370, chr15-CpG: 32/Downstream/326120
Upstream sequence
tgccttatttgactaacatgcccctaaccccccagcccacagcctcttgtaaccacTTAAGAATTCTCTTAAGAGATTTTTGTATGAGAtttgggttgtg
Downstream sequence
aagtatctgctgccattgcacatttcatttaaagtaaggataatgggatttgattgactttctaagtgtagtagagaatttgaagaCccacagagtctac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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