Basic Information
VIS ID
TVIS44021000
Fusion event
HTLV-1-LUNAR1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
99558341/99015112 (Hg38)
End
99558341/99015112 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LUNAR1
Nearest miRNA
hsa-mir-10393/Upstream/230610; hsa-mir-1302-10/Downstream/2945347;
Nearest TSS
ENST00000557528/Upstream/7317; ENST00000611654/Downstream/13426;
Nearest CpG islands
chr15-CpG: 112/Target, None/Upstream, None/Downstream
Upstream sequence
CGCGCACCTGTTGTTGCCTCGGGACTGAACTGCAGCGGCGGACCGGCGAGCGGGGGGCCTGGACGTCGAGTgcggggccggcggggcccccgcACTCACC
Downstream sequence
CTCGGGAGCGTTTAAGTCCCTCCCGGGAAGAAGGGGGAGGAAATGCTCGGGGGAGCCGGAAGAGGCACTGCCAGCATCAACTCCACGCGCGCCCCGGCCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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