Basic Information
VIS ID
TVIS44021011
Fusion event
HTLV-1-SLC5A11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
24895830/24884509 (Hg38)
End
24895830/24884509 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA16E
Target gene
SLC5A11
Nearest miRNA
hsa-mir-1225/Upstream/681278; hsa-mir-11401/Downstream/1140728;
Nearest TSS
ENST00000527434/Upstream/7405; ENST00000571219/Downstream/36495;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/154028, chr16-CpG: 66/Downstream/130237
Upstream sequence
agccttgagcccctgggctcaagtgactctctcacctcagcctcctgagtagctgggactacagacataggccactatgtcgagctaattgcttttttat
Downstream sequence
tttgttttttttttttttttttgtagagatagagtctcactatgttgcccaggctgatctcaaactcctggcctcaagtgattctcctgcctcagcctcc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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