VISDB Viral Integration Site DataBase

VIS ID

TVIS44021025

Fusion event

HTLV-1-ORC6 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr16

Cytoband

q11.2

Reference genome

Start

End

46731280/46697368 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-92a-3p ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-4746-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-6741-3p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-3135b ; hsa-mir-6836-3p ; hsa-mir-5001-3p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-4284 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-4772-3p ; hsa-mir-532-3p ; hsa-mir-1304-3p ; hsa-mir-662 ; hsa-mir-6890-3p ; hsa-mir-548s ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-3926 ; hsa-mir-6134 ; hsa-mir-7854-3p ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-3190-5p ; hsa-mir-7162-3p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-1587 ; hsa-mir-194-3p ; hsa-mir-3620-5p ; hsa-mir-4252 ; hsa-mir-4417 ; hsa-mir-4486 ; hsa-mir-4492 ; hsa-mir-4498 ; hsa-mir-4649-5p ; hsa-mir-4656 ; hsa-mir-4675 ; hsa-mir-4741 ; hsa-mir-4793-3p ; hsa-mir-5001-5p ; hsa-mir-508-5p ; hsa-mir-6499-3p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6729-5p ; hsa-mir-6829-5p ; hsa-mir-762 ; hsa-mir-766-3p ; hsa-mir-7703 ; hsa-mir-939-3p

Nearest miRNA

hsa-mir-1225/Upstream/12533695; hsa-mir-11401/Downstream/3595248;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/7173, chr16-CpG: 39/Downstream/92551

Upstream sequence

gaacctaggaatttgagtgcagcctgagcaacattacaagaccccatctcaaaaaaaaGTGATAACTGCTGTTTCTCCATGTCATTTCAGTATCTTTTCT

Downstream sequence

ATTTTAGACAATTTAAACAAGTTTACCTTTTTTTAAATTTCATTTCTAAGCTAAGAATTTTGAAATTGCTTTTGATAATTTTCTGTCAGAAATGGAGAAG