Basic Information
VIS ID
TVIS44021050
Fusion event
HTLV-1-chr16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q21
Reference genome
GRCh37/hg19
Start
60738185/60704281 (Hg38)
End
60738185/60704281 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/2931929; hsa-mir-11401/Downstream/6498040;
Nearest TSS
ENST00000527434/Upstream/181031; ENST00000562349/Downstream/1009777;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/949113, chr16-CpG: 117/Downstream/1330936
Nearby gene
NPAP1L(-344518) ;
Upstream sequence
tcacttgcaATAGTCATTATCAGACAAGTACCAATGAGATACATTAAAAAATCAAGAACTATGGAATATATTTTAAATCAAATTAATACATTTGTGATTA
Downstream sequence
AATCCATTTATGTCACTCATGTGGACTTACACAAGCTGTTTCAGAGCCATTATTTTCAAAGAGAAGTCAGGGTTTATTGGAAACATATCCATtgtgtaca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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