Basic Information
VIS ID
TVIS44021064
Fusion event
HTLV-1-JMJD8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
731884/681884 (Hg38)
End
731884/681884 (Hg38)
Orient
-
Location type
UTR3
Target gene
JMJD8
miRNAs that regulate target gene
hsa-mir-93-3p
Nearest miRNA
hsa-mir-3176/Upstream/138518; hsa-mir-11401/Downstream/88299;
Nearest TSS
ENST00000527434/Upstream/403; ENST00000565813/Downstream/532;
Nearest CpG islands
chr16-CpG: 486/Target, None/Upstream, None/Downstream
Upstream sequence
ACCCCCAGGGAGCTGGAAGAGTGCCAGCGAAACCACGAGGGTGATGAGGACGACAGCCACGTCCGGGCCCAGCAGGCCTGCATTGAGGCCAAGCACGTGA
Downstream sequence
GGGTGCCCCCCACCCACATGTGGGTCTGTGTGTGTGCACGTGGCGTGGGAGCATCCCCGCCTTGTGTTGGGTCTGTGCCCCATGGAGGAGGGAGGTGGGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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