VISDB Viral Integration Site DataBase

VIS ID

TVIS44021068

Fusion event

HTLV-1-ZFHX3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr16

Cytoband

q22.3

Reference genome

Start

End

73031295/72997396 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-340-5p ; hsa-mir-103a-3p ; hsa-mir-98-5p ; hsa-mir-16-5p ; hsa-mir-532-5p ; hsa-mir-181b-5p ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-3681-3p ; hsa-mir-138-2-3p ; hsa-mir-5011-5p ; hsa-mir-486-3p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-1468-3p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-211-3p ; hsa-mir-545-3p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-6805-5p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-548p ; hsa-mir-4511 ; hsa-mir-4449 ; hsa-mir-3163 ; hsa-mir-2114-5p ; hsa-mir-4760-3p ; hsa-mir-5588-3p ; hsa-mir-548c-3p ; hsa-mir-190a-3p ; hsa-mir-4470 ; hsa-mir-205-3p ; hsa-mir-1277-5p ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-5197-5p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-623 ; hsa-mir-513a-5p ; hsa-mir-642b-5p ; hsa-mir-630 ; hsa-mir-676-5p ; hsa-mir-6832-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-3973 ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-4729 ; hsa-mir-5000-5p ; hsa-mir-6502-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-4668-3p ; hsa-mir-1250-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-4711-5p ; hsa-mir-7112-3p ; hsa-mir-7844-5p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-129-5p ; hsa-mir-487a-5p ; hsa-mir-487b-5p ; hsa-mir-659-3p

Nearest miRNA

hsa-mir-1225/Upstream/2966974; hsa-mir-11401/Downstream/3871540;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/37428, chr16-CpG: 106/Downstream/50295

Nearest cancer related gene

ZFHX3(TSG, No orient, 0)

Upstream sequence

AACCGGATTCTGAGGGTCCAGACGTCTCTGTTTGAGCAACAGCTGCCTTCCTTTAAAGGTCCCACAGTTGAGCAATAGAGTTCTTTACTCAAGAGGGCTG

Downstream sequence

TTCCAAGTCTTGAGTAACCACCCTTGCCCTCAAGGGTTCCCCAGGGTGAAGCCCCATTGCCTCTGCCTCACCAAGGAGGCAGCGACTCAGTCTTCTCGCT