Basic Information
VIS ID
TVIS44021071
Fusion event
HTLV-1-LOC105371349 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
76125606/76091708 (Hg38)
End
76125606/76091708 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105371349
Nearest miRNA
hsa-mir-1225/Upstream/6061286; hsa-mir-11401/Downstream/777228;
Nearest TSS
ENST00000527434/Upstream/230841; ENST00000463177/Downstream/56071;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/443027, chr16-CpG: 18/Downstream/143371
Nearby gene
CNTNAP4(+185570) ;
Upstream sequence
GCATACTCTTCCACTTTTCCAGACTTGCTTCCTCAAACAGTCATATTGTGCCATTAGCAAATTGTTTCTGGTTTCTGCATCTATCATTTAGTTAGCTCAT
Downstream sequence
GAGACTGCTGTTTGGTCAGACTTGATAAAGAAATCTTGTCTGTGCTGTatgtggcattggtcaggatggcttgtgtgggggcagattctacttttaggat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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