Basic Information
VIS ID
TVIS44021074
Fusion event
HTLV-1-MON1B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q23.1
Reference genome
End
77229932/77196035 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-93-3p ; hsa-mir-99a-5p ; hsa-mir-6760-5p ; hsa-mir-3940-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-466 ; hsa-mir-5011-5p ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-5580-3p ; hsa-mir-6514-3p ; hsa-mir-3161 ; hsa-mir-4633-5p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-8088 ; hsa-mir-598-5p ; hsa-mir-532-5p ; hsa-mir-216b-5p ; hsa-mir-216a-5p ; hsa-mir-6507-5p ; hsa-mir-548at-5p ; hsa-mir-3591-5p ; hsa-mir-142-3p ; hsa-mir-3941 ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-3920 ; hsa-mir-648 ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-32-3p ; hsa-mir-3924 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-2053 ; hsa-mir-4775 ; hsa-mir-569 ; hsa-mir-6878-3p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-4454 ; hsa-mir-3150b-5p ; hsa-mir-3150a-5p ; hsa-mir-6749-3p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-4469 ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-5001-3p ; hsa-mir-4727-5p ; hsa-mir-92b-5p ; hsa-mir-3912-5p ; hsa-mir-502-5p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-198 ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-8063 ; hsa-mir-4668-3p ; hsa-mir-4443 ; hsa-mir-6515-5p ; hsa-mir-670-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-4526 ; hsa-mir-3660 ; hsa-mir-4319 ; hsa-mir-125b-5p ; hsa-mir-125a-5p ; hsa-mir-4732-3p ; hsa-mir-345-3p ; hsa-mir-2114-5p ; hsa-mir-1178-3p ; hsa-mir-129-5p ; hsa-mir-3120-5p ; hsa-mir-3664-5p ; hsa-mir-4639-3p ; hsa-mir-6740-3p ; hsa-mir-6794-3p ; hsa-mir-6885-3p ; hsa-mir-6888-3p ; hsa-mir-937-3p
Nearest miRNA
hsa-mir-1225/Upstream/327016; hsa-mir-11401/Downstream/4188983;
Upstream sequence
TTTGACTTTCCAGAGGCCCCATTAACTACCACTGCTGTGCCTGCCGATTCCCCAGTAGCCCAATCCATGTGTTTGGAGGcaccccattcatcaccagctc
Downstream sequence
attgtgactccatgagtccccagcactcctcagactacaggcgtggtcccttgctgtgccctccacctggggtatccttccctttggtctcctctgggct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate