Basic Information
VIS ID
TVIS44021081
Fusion event
HTLV-1-CMC2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
81016611/80983006 (Hg38)
End
81016611/80983006 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA16D
Target gene
CMC2
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1225/Upstream/4113987; hsa-mir-11401/Downstream/402012;
Nearest TSS
ENST00000527434/Upstream/90411; ENST00000568445/Downstream/329;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/50425, chr16-CpG: 122/Downstream/23405
Upstream sequence
tggaagtgctcccaagaagcagagaaaagtaatgacattacaggaaaaagttgaactacttgaaatgtactgtagattgaggtctgcagctgtggttacc
Downstream sequence
taccatttcggactgacatacatcatcttgtaaacagatgatgtaaacttacaatatcaataaatacaataccataccataaatgtattttctcttcctt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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