Basic Information
VIS ID
TVIS44021096
Fusion event
HTLV-1-chr16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
85923764/85890158 (Hg38)
End
85923764/85890158 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12128/Upstream/148458; hsa-mir-11401/Downstream/28189;
Nearest TSS
ENST00000527434/Upstream/85089; ENST00000565552/Downstream/8645;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/60163, chr16-CpG: 100/Downstream/8357
Nearby gene
IRF8(+9010) ;
Nearest cancer related gene
IRF8(TSG, +9010) ;
Upstream sequence
CAAAATCATCCGTCTTGTCTCTAAGTGCCAGGGTAAAAATGGACTTCTAGGATTGCATTTAAAAATATCTCTAACCACGCTCAAAGTTTGTGATTCTCCT
Downstream sequence
TAGAGGTAAATTATTGTTGTTGTATTGATATTTTATTGTGCTTCTGCCATTTGTTTCTCACAGATGCACCTGCTGCACATCTGCAAAGGTAAGCTGGAGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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