VISDB Viral Integration Site DataBase

VIS ID

TVIS44021110

Fusion event

HTLV-1-MYO1C integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr17

Cytoband

p13.3

Reference genome

Start

End

1367489/1464195 (Hg38)

Orient

+

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-34a-5p ; hsa-mir-18a-3p ; hsa-mir-324-5p ; hsa-mir-181b-5p ; hsa-mir-92a-3p ; hsa-mir-27a-3p ; hsa-let-7b-5p ; hsa-mir-6825-5p ; hsa-mir-7106-5p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-3202 ; hsa-mir-3179 ; hsa-mir-4646-5p ; hsa-mir-204-3p ; hsa-mir-582-3p ; hsa-mir-548e-5p ; hsa-mir-765 ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-6807-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-193b-5p ; hsa-mir-5589-5p ; hsa-mir-7155-5p ; hsa-mir-4731-5p ; hsa-mir-6872-3p ; hsa-mir-6849-3p ; hsa-mir-4438 ; hsa-mir-4309 ; hsa-mir-3198 ; hsa-mir-6509-3p ; hsa-mir-4668-5p ; hsa-mir-4294 ; hsa-mir-1289 ; hsa-mir-1287-5p ; hsa-mir-3135b ; hsa-mir-5702 ; hsa-mir-570-3p ; hsa-mir-3692-5p ; hsa-mir-1273g-3p ; hsa-mir-6754-5p ; hsa-mir-181a-2-3p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-211-3p ; hsa-mir-5584-5p ; hsa-mir-137 ; hsa-mir-4444 ; hsa-mir-924 ; hsa-mir-9-5p

Nearest miRNA

hsa-mir-3183/Upstream/441636; hsa-mir-10226/Downstream/249708;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/7675, chr17-CpG: 22/Downstream/7727

Upstream sequence

cgagactgtctcgagaaaaaCCTGCAACACGAGGCCCTTGGTTGCCTTCCGGGGCCCTCTTCGTTTCCTAATATTCATAAGGAGACCACATTGGCAAACA

Downstream sequence

CGTATTGCTTTATTTAGTGTTTCTCTGGATTGCAGAAGTGTCAGCAGTGGGCTGAGACCCCCAGAAGGGCATAGAGGCAGCTGGGCAGCCCCCAGGCCCT