Basic Information
VIS ID
TVIS44021115
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
21223336/21320024 (Hg38)
End
21223336/21320024 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/1975450; hsa-mir-10226/Downstream/5973886;
Nearest TSS
ENST00000595228/Upstream/7882; ENST00000331718/Downstream/56173;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/2924, chr17-CpG: 135/Downstream/56022
Nearby gene
MAP2K3(+4785) ;
Upstream sequence
CTCTGTCCTCGCAGAAGCCGTGGGCTGCTCTATTCCTGTTCTGGGCCAGCCTTATTGGGGACTTGAGTTGGGGAGGCCTGGCGAGGCAGCAGCAGCTGCA
Downstream sequence
AGCTCTGGTTGGGGATGGGGGAGTTGCTCTGTGAACTAGCCTAGGAAATTCTTTCCTTGTCTGCCTCCCAAACCCTCCATGGCTCCCTATTCCCACAACA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate