Basic Information
VIS ID
TVIS44021118
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
2284853/2381559 (Hg38)
End
2284853/2381559 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-132/Upstream/331179; hsa-mir-10226/Downstream/311302;
Nearest TSS
ENST00000595228/Upstream/2253; ENST00000571775/Downstream/3288;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/9100, chr17-CpG: 197/Downstream/11069
Nearby gene
SGSM2(+505) ;
Upstream sequence
AGAGGCCGGAGGGGAGTGTCAGGAGGAGTCAGACCCTGCTGAGCTATAGACAGGCCCAGCTGTAACGGGTCTGCACCTCTCTTCCTGCCCTTCCCCAACC
Downstream sequence
CGAGTGCTACTGGTCCCATCGTCGATGGCTCCAGGGAGAAGACACCAGTCACACAACATGTCTTCTACCCTAGAGGACACTGGCTTCCTGGACATTAGGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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