Basic Information
VIS ID
TVIS44021119
Fusion event
HTLV-1-MNT integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.3
Reference genome
End
2290661/2387367 (Hg38)
Orient
-
Location type
Exonic
Target gene
miRNAs that regulate target gene
hsa-mir-210-3p ; hsa-mir-331-3p ; hsa-mir-17-5p ; hsa-mir-218-5p ; hsa-mir-3691-5p ; hsa-mir-3165 ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-486-3p ; hsa-mir-6883-5p ; hsa-mir-6825-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-885-3p ; hsa-mir-1255b-5p ; hsa-mir-1255a ; hsa-mir-6744-5p ; hsa-mir-3656 ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-6889-5p ; hsa-mir-6777-5p ; hsa-mir-211-3p ; hsa-mir-1272 ; hsa-mir-4688 ; hsa-mir-6743-5p ; hsa-mir-92b-5p ; hsa-mir-3674 ; hsa-mir-3692-3p ; hsa-mir-4703-3p ; hsa-mir-922 ; hsa-mir-3118 ; hsa-mir-134-5p ; hsa-mir-4483 ; hsa-mir-1293 ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-5589-5p ; hsa-mir-7112-3p ; hsa-mir-6774-5p ; hsa-mir-5002-3p ; hsa-mir-635 ; hsa-mir-6776-5p ; hsa-mir-3614-5p ; hsa-mir-4446-3p ; hsa-mir-6807-5p ; hsa-mir-4539 ; hsa-mir-146a-3p ; hsa-mir-6777-3p ; hsa-mir-4714-5p ; hsa-mir-1343-5p ; hsa-mir-187-3p ; hsa-mir-198 ; hsa-mir-3150a-3p ; hsa-mir-3175 ; hsa-mir-3657 ; hsa-mir-3660 ; hsa-mir-4526 ; hsa-mir-4537 ; hsa-mir-4669 ; hsa-mir-491-5p ; hsa-mir-6719-3p ; hsa-mir-6730-3p ; hsa-mir-6763-5p ; hsa-mir-6827-5p ; hsa-mir-92a-2-5p ; hsa-mir-939-5p ; hsa-mir-1207-5p ; hsa-mir-1908-5p ; hsa-mir-3141 ; hsa-mir-4270 ; hsa-mir-4434 ; hsa-mir-4441 ; hsa-mir-4516 ; hsa-mir-4723-5p ; hsa-mir-4763-3p ; hsa-mir-5090 ; hsa-mir-5698 ; hsa-mir-5703 ; hsa-mir-6090 ; hsa-mir-6132 ; hsa-mir-663a ; hsa-mir-6721-5p ; hsa-mir-6754-5p ; hsa-mir-6775-5p ; hsa-mir-6787-5p ; hsa-mir-6816-5p ; hsa-mir-6836-5p ; hsa-mir-6870-5p ; hsa-mir-6878-5p ; hsa-mir-7111-5p ; hsa-mir-744-5p ; hsa-mir-1915-3p ; hsa-mir-4426 ; hsa-mir-4433a-5p ; hsa-mir-4433b-5p ; hsa-mir-4647 ; hsa-mir-4662b ; hsa-mir-4726-3p ; hsa-mir-574-5p ; hsa-mir-576-3p ; hsa-mir-6764-5p ; hsa-mir-6840-3p ; hsa-mir-6867-5p
Nearest miRNA
hsa-mir-132/Upstream/336987; hsa-mir-10226/Downstream/305494;
Nearest cancer related gene
MNT(TSG, No orient, 0)
Upstream sequence
CCCTGCAGAACGTGGTTCACAGTCTGGATGACTGAAGCGTGAGTGGTGGCTGTGTGGGCGATGACCGTGGAGCCACCCCCAGCCGTCGCCACCAGATGGG
Downstream sequence
CTGGAGCTGGCACCAGTGTCTGGGCAGGGGCAGCCGGTGGGGGAGGAGGGGCTGGCAGAGGGGTCTTCTGCTGTGGCTGCTGCTGCTGCACGGggaggtg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate