Basic Information
VIS ID
TVIS44021121
Fusion event
HTLV-1-CCDC92B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
2624748/2721454 (Hg38)
End
2624748/2721454 (Hg38)
Orient
+
Location type
Intronic
Target gene
CCDC92B
Nearest miRNA
hsa-mir-132/Upstream/28535; hsa-mir-10226/Downstream/26624;
Nearest TSS
ENST00000595228/Upstream/8791; ENST00000609567/Downstream/2493;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/9118, chr17-CpG: 114/Downstream/2553
Nearby gene
CLUH(No orient, 9821)
Upstream sequence
TCTCTCTCCCAATGGGGATTCGTGCAGCAGAGGAGAGAGAAATGCAGTCCTTTCCCTTCTTAGTCACCAAGATATTCCAGGGGCCAGGAGCGCGTGGGGG
Downstream sequence
TGCGAGGTTTCCCTTTGGCCAGGTGGGCTCTCAAGCCAGACCCAGGGAGGGTGGGGCCTCTCCAGGGCCCTGAGGCTGAGGAGAGTTGGGCCCCTGTGGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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