Basic Information
VIS ID
TVIS44021125
Fusion event
HTLV-1-LRRC37BP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
28962139/30635121 (Hg38)
End
28962139/30635121 (Hg38)
Orient
-
Location type
ncRNA_exonic
Target gene
LRRC37BP1
Nearest miRNA
hsa-mir-1180/Upstream/517949; hsa-mir-10226/Downstream/459229;
Nearest TSS
ENST00000595228/Upstream/69545; ENST00000581019/Downstream/92443;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/33685, chr17-CpG: 30/Downstream/70870
Upstream sequence
TTCCAGCCACAGCAGCCCCTCAGCGTCCCCCAGTCACACTGTCCCCATTGCTGCTCATCTGTGCCTTTGTCCATCTACAATGCCCTTATTTCACTCTGCC
Downstream sequence
TGTGGGAGTCCTGTGAATCTCTCCAAAGCCAACTCAGTTCATCTTTCTGCTTGAAACCTTCCCTGAATAggccaggtgcggtggctcacgcctgtaatcc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate