Basic Information
VIS ID
TVIS44021140
Fusion event
HTLV-1-MAPT-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
43929292/45851926 (Hg38)
End
43929292/45851926 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
MAPT-AS1
Nearest miRNA
hsa-mir-1180/Upstream/376491; hsa-mir-10226/Downstream/1121091;
Nearest TSS
ENST00000595228/Upstream/7091; ENST00000571311/Downstream/42456;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/66364, chr17-CpG: 320/Downstream/42118
Upstream sequence
CCCCAGGGCCCCAGGTGGCCCAGCCTCAGGGTCGAGCTGTTTTACACAGGCCAACTGGCATTTCTGTCTGTGACCTTGGTAATCCCAGCACCAGCTTTAT
Downstream sequence
GAGCATGGGCTTGGTTTTCTTTTGTTCATGAGAGGGTTTAGTACTGGAGCTTCTGGATTTCTGGGACAgtggggaccagcaaggacctgtgagatgatct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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