VISDB Viral Integration Site DataBase

VIS ID

TVIS44021141

Fusion event

HTLV-1-PELP1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr17

Cytoband

p13.2

Reference genome

Start

End

4579162/4675867 (Hg38)

Orient

+

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-9-5p ; hsa-mir-744-5p ; hsa-mir-615-3p ; hsa-mir-193b-3p ; hsa-mir-423-3p ; hsa-mir-18a-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-190a-3p ; hsa-mir-466 ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-5011-5p ; hsa-mir-5580-3p ; hsa-mir-4643 ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-1277-5p ; hsa-mir-377-3p ; hsa-mir-3074-3p ; hsa-mir-8064 ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-7852-3p ; hsa-mir-802 ; hsa-mir-4528 ; hsa-mir-323a-3p ; hsa-mir-1273h-5p ; hsa-mir-149-3p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-2467-3p ; hsa-mir-30b-3p ; hsa-mir-3160-3p ; hsa-mir-3192-5p ; hsa-mir-3612 ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-377-5p ; hsa-mir-4252 ; hsa-mir-4257 ; hsa-mir-4329 ; hsa-mir-4487 ; hsa-mir-455-3p ; hsa-mir-4728-5p ; hsa-mir-4786-5p ; hsa-mir-490-3p ; hsa-mir-558 ; hsa-mir-591 ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-6502-3p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6516-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6799-5p ; hsa-mir-6872-3p ; hsa-mir-6883-5p ; hsa-mir-7106-5p ; hsa-mir-769-5p ; hsa-mir-7851-3p ; hsa-mir-4282

Nearest miRNA

hsa-mir-1253/Upstream/1927685; hsa-mir-10226/Downstream/293835;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/34228, chr17-CpG: 70/Downstream/27822

Nearest cancer related gene

PELP1(OG, No orient, 0)

Upstream sequence

GCTCTGAAGAGATGACAAATCCCACTTACAATATTCTTGCTACTGACGCTGAGGGTCCGGCAGATGAAATCCAGGATTTCCTGCACAGGGACGGACACGG

Downstream sequence

GAGCTCCAAACTCAGAGCTAAAGAGAATCAGAGCAGGGAGACCTTCAGAGCAGGCTCCCTGGCATAACTCCCACACCCACCTTCATCTCCTTTCTCCTGA