Basic Information
VIS ID
TVIS44021147
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q22
Reference genome
GRCh37/hg19
Start
53323077/55245716 (Hg38)
End
53323077/55245716 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10226/Upstream/4476986; hsa-mir-1250/Downstream/1645554;
Nearest TSS
ENST00000595228/Upstream/214909; ENST00000572234/Downstream/19296;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/6879, chr17-CpG: 88/Downstream/19121
Nearby gene
HLF(+19244) ;
Nearest cancer related gene
HLF(OG, +19244) ;
Upstream sequence
TATTTACTCTATAGAGAATACATTTTGTTTAAGTGCTGAAACGTTTATAAGAGTTACTCTTTTTTTCATAGTTTTATATCAATGAGATAAATTCAAAAGG
Downstream sequence
AAATCGACTAATTTTGGAAGGCTCATATTTGCCTCTTTGTCTTATTATGTCCCTAATATCACATATTGGGACTCAAATACACATTTGATAAATTATCAGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate