Basic Information
VIS ID
TVIS44021155
Fusion event
HTLV-1-PITPNM3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
End
6359666/6456346 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-6742-3p ; hsa-mir-4646-3p ; hsa-mir-96-5p ; hsa-mir-1271-5p ; hsa-mir-182-5p ; hsa-mir-4433b-5p ; hsa-mir-4507 ; hsa-mir-3940-5p ; hsa-mir-7150 ; hsa-mir-6793-5p ; hsa-mir-494-5p ; hsa-mir-410-5p ; hsa-mir-323b-5p ; hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-6799-5p ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-4722-5p ; hsa-mir-6134 ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4768-3p ; hsa-mir-4419a ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6873-5p ; hsa-mir-4776-3p ; hsa-mir-4659b-5p ; hsa-mir-4659a-5p ; hsa-mir-5590-5p ; hsa-mir-5189-3p ; hsa-mir-339-3p ; hsa-mir-6888-3p ; hsa-mir-6873-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-6740-3p ; hsa-mir-3670 ; hsa-mir-3120-5p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-556-5p ; hsa-mir-6741-3p ; hsa-mir-6867-3p ; hsa-mir-642a-5p ; hsa-mir-6845-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-7152-5p ; hsa-mir-511-5p ; hsa-mir-5001-3p ; hsa-mir-6830-3p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-6728-3p ; hsa-mir-3667-3p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-4753-3p ; hsa-mir-130b-5p ; hsa-mir-6847-3p ; hsa-mir-6747-3p ; hsa-mir-629-3p ; hsa-mir-4713-5p ; hsa-mir-183-5p ; hsa-mir-4707-3p ; hsa-mir-593-5p ; hsa-mir-6771-3p ; hsa-mir-7108-3p
Nearest miRNA
hsa-mir-1253/Upstream/1486196; hsa-mir-10226/Downstream/199094;
Upstream sequence
accctgggctcaagcaatcctgcgtatcaaagcaccaggattacaggcatgagccagggtgcttggccTCTGGATTCTTGAGGGTGGGGAAGCGCCCATC
Downstream sequence
CTTGTCACTTGGCTCACTAGAATCCTGCAAAGTCCCTCCCGTCACGCAGCCTCACCATGCCTCTTGTCATTTTTCTGAGCCCTGCGACTGCCCTCCTTGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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