Basic Information
VIS ID
TVIS44021185
Fusion event
HTLV-1-STX8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
9473678/9570361 (Hg38)
End
9473678/9570361 (Hg38)
Orient
+
Location type
Intronic
Target gene
STX8
Nearest miRNA
hsa-mir-1253/Upstream/1383357; hsa-mir-10226/Downstream/2511538;
Nearest TSS
ENST00000595228/Upstream/419; ENST00000576499/Downstream/5450;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/329839, chr17-CpG: 26/Downstream/5329
Upstream sequence
ATAATTATAGCAATAGTAACAGCTGAGTACCTGACCTGAGCCAGGTCCTATACTAAGAGCTTTACACTGTAAACTTCATAAGGATCCTGAGAGAGGATCC
Downstream sequence
TGAACCACTAACCACTATACTGTAAAGCAGCACCATTCatgtatatatcatatatatatcacacacattcacatatatcatatatatcactgatacatat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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