Basic Information
VIS ID
TVIS44021187
Fusion event
HTLV-1-ANKRD62 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
12167416/12167417 (Hg38)
End
12167416/12167417 (Hg38)
Orient
+
Location type
Intronic
Target gene
ANKRD62
miRNAs that regulate target gene
hsa-mir-619-5p ; hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-556-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-550a-5p ; hsa-mir-550a-3-5p ; hsa-mir-1271-3p ; hsa-mir-874-5p ; hsa-mir-661 ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-640 ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-3157-5p ; hsa-mir-4735-5p ; hsa-mir-6872-3p ; hsa-mir-767-5p ; hsa-mir-378a-5p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3653-5p ; hsa-mir-1976 ; hsa-mir-4279 ; hsa-mir-4722-3p ; hsa-mir-4740-3p ; hsa-mir-485-3p ; hsa-mir-539-3p ; hsa-mir-6512-5p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6778-3p
Nearest miRNA
hsa-mir-3976/Upstream/512476; hsa-mir-1-2/Downstream/1292530;
Nearest TSS
ENST00000575820/Upstream/64711; ENST00000592203/Downstream/33362;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/73574, chr18-CpG: 90/Downstream/86731
Nearby gene
C18orf61(No orient, 33362)
Upstream sequence
atgttccctgccctgtgtccaagcgttctcattgttcagttcccacctatgagtgagaacatgtggtgtttggttttctgtccttgtgatagtttgctca
Downstream sequence
gaatgatgatttccggcttcatccatgtcgctacaaaggacatgaactcatccttttttatggctgcatagtattccatggtgtatatgtgccacatttt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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