Basic Information
VIS ID
TVIS44021188
Fusion event
HTLV-1-LINC00470 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.32
Reference genome
GRCh37/hg19
Start
1309865/1309864 (Hg38)
End
1309865/1309864 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC00470
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-8078/Upstream/1197525; hsa-mir-1-2/Downstream/2575489;
Nearest TSS
ENST00000575820/Upstream/150723; ENST00000583163/Downstream/48898;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/400291, chr18-CpG: 33/Downstream/1261423
Upstream sequence
CCACTGGGAACTGTGGTCTCAAACCTTCATGCCCTGTGAACAGCTCAACTTCTTCGAACTGCCAACATATTCACCAACAGAAACCAGGATCTTCCAAAGG
Downstream sequence
GAGTCCATGTCTTTCTATCTAGATCTAACTAAAGGACCAATTCACCGAAAAAGTAATAatctactttacacatggtgactatagttaatatcaatacatt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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