Basic Information
VIS ID
TVIS44021196
Fusion event
HTLV-1-LINC01894 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
22516635/24936671 (Hg38)
End
22516635/24936671 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC01894
Nearest miRNA
hsa-mir-1-2/Upstream/614925; hsa-mir-122/Downstream/1654796;
Nearest TSS
ENST00000575820/Upstream/210727; ENST00000578129/Downstream/50994;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/509628, chr18-CpG: 113/Downstream/412544
Nearby gene
ZNF521(-125253) ;
Upstream sequence
AAGAAGGCAAAGAGAATACTGTCCCAGTGTATATCTGCACCCCTTTGTCTGGGCACTGAAAGGTCACAGATACCACTGGCCTTCCTGTTGAGCCACTCTG
Downstream sequence
AATTTAATCTGTTGGGTTTGATTTGCTGAATGTATATGCACGTCAAAGATTGTGAGCATGGATTATTTATAAGATGTTCACTTCCAATTAGTGTGGCTTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate