Basic Information
VIS ID
TVIS44021228
Fusion event
HTLV-1-SLC14A2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
43178214/45598249 (Hg38)
End
43178214/45598249 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLC14A2
Nearest miRNA
hsa-mir-1-2/Upstream/628083; hsa-mir-122/Downstream/1782247;
Nearest TSS
ENST00000575820/Upstream/115031; ENST00000323329/Downstream/16552;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/534277, chr18-CpG: 37/Downstream/177104
Upstream sequence
CCTCAAGGGCCTTCTAGTCAAAATGGAGCCAGCCAGCCCCGACTGTTAGCGTGTCTGTGCCCACGTAGGTTATCTCTGTCTCATTTTACCCATCAGAATA
Downstream sequence
GATTACCGAGAAGCTCCAGTTCCCTGTTTGAAATGATCTCTCTGTAGAAACAAAAAGACATTCAAGACCCGAGGGCTTCAAAGCAGTGGAGAAGGGGAGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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