Basic Information
VIS ID
TVIS44021245
Fusion event
HTLV-1-LINC01539 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
53777979/56110748 (Hg38)
End
53777979/56110748 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA18B
Target gene
LINC01539
Nearest miRNA
hsa-mir-1-2/Upstream/631450; hsa-mir-122/Downstream/2340326;
Nearest TSS
ENST00000575820/Upstream/924; ENST00000590589/Downstream/26601;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/330137, chr18-CpG: 57/Downstream/527440
Upstream sequence
CTCTGGAAGACCCAGACCAGAAAGTTTGCACAAGACGTCTACATTGTCACAATCAGGTGCCATTCTTATTATTTAAATCAACTTCTAAATGGCCACTTGA
Downstream sequence
GTTTTGACAGAAATCTGTTCTAGAATTTAGCAAATGCAGAGAATGAAAAGAAATTCTGTCGCAGAGCCCAGTCTCTAAAGGCAGCAGGTGGGAGCCAGTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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