Basic Information
VIS ID
TVIS44021252
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
55053321/57386089 (Hg38)
End
55053321/57386089 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA18B
Nearest miRNA
hsa-mir-1-2/Upstream/1906791; hsa-mir-122/Downstream/1064985;
Nearest TSS
ENST00000575820/Upstream/22576; ENST00000620778/Downstream/41044;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/31715, chr18-CpG: 164/Downstream/41504
Nearby gene
ST8SIA3(+17160) ;
Upstream sequence
AAGGGAGGGAAGAGGAAGGAGGGTAGCTTTTCTATTTGTCAGTTTTTTTCCATCTCTGTGCAAACCAAATCTAAGTCAAGGCCAACCCGATTTTCCTATG
Downstream sequence
AATTCAAATTCTCCATTCCTTGTAAGATTTAGCCAAGGAGACATCTCCTCCAGGATGTCTGCCTAGGCTACATTTACCCCCATGAGATCTTTGCATGCTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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