Basic Information
VIS ID
TVIS44021265
Fusion event
HTLV-1-CCDC102B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
66754226/69086989 (Hg38)
End
66754226/69086989 (Hg38)
Orient
+
Location type
Intronic
Target gene
CCDC102B
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-mir-1-2/Upstream/2005303; hsa-mir-548av/Downstream/3766332;
Nearest TSS
ENST00000575820/Upstream/184734; ENST00000579651/Downstream/125288;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/371651, chr18-CpG: 174/Downstream/313284
Nearby gene
CCDC102B(+31800) ;
Upstream sequence
AGAAGGACTTAAACACTGTTAAGTGTTTCAAAAGATGCTATTTAGTTATTTTTAAATCCTTATGACATCTGAATAAATGTTTCTTCCATTGAAGGTGAAA
Downstream sequence
ACATTTACTGTTTGCCCATAGATAAAAATGGGCAAAATATTGGCATTATTAGATTATATTATTTTTTCTTTTCATTGTTTTTTATTGATTTCTATCCTAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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