VISDB Viral Integration Site DataBase

VIS ID

TVIS44021290

Fusion event

HTLV-1-F2RL3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr19

Cytoband

p13.11

Reference genome

Start

End

17000571/16889760 (Hg38)

Orient

-

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-657 ; hsa-mir-3665 ; hsa-mir-1205 ; hsa-mir-125a-3p ; hsa-mir-9500 ; hsa-mir-4779 ; hsa-mir-596 ; hsa-mir-500a-3p ; hsa-mir-6807-5p ; hsa-mir-8077 ; hsa-mir-7160-5p ; hsa-mir-4663 ; hsa-mir-6778-3p ; hsa-mir-4252 ; hsa-mir-5186 ; hsa-mir-6804-3p ; hsa-mir-3130-3p ; hsa-mir-1273g-3p ; hsa-mir-1295b-3p ; hsa-mir-759 ; hsa-mir-512-3p ; hsa-mir-3186-5p ; hsa-mir-5089-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6781-3p ; hsa-mir-2682-3p ; hsa-mir-302a-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-498 ; hsa-mir-6878-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-6815-3p ; hsa-mir-8073 ; hsa-mir-221-5p

Nearest miRNA

hsa-mir-10395/Upstream/1440152; hsa-let-7e/Downstream/1392317;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/10871, chr19-CpG: 66/Downstream/56

Upstream sequence

CTCACGGGCACTGCTTCTGGGCTGGGTGCCCACCAGGCTGGTGCCCGCCCTCTATGGGCTGGTCCTGGTGGTGGGGCTGCCGGCCAATGGGCTGGCGCTG

Downstream sequence

TGGGTGCTGGCCACGCAGGCACCTCGGCTGCCCTCCACCATGCTGCTGATGAACCTCGCGGCTGCTGACCTCCTGCTGGCCCTGGCGCTGCCCCCGCGGA