Basic Information
VIS ID
TVIS44021332
Fusion event
HTLV-1-NAPSB integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
50841013/50337756 (Hg38)
End
50841013/50337756 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA19A
Target gene
NAPSB
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10395/Upstream/404619; hsa-let-7e/Downstream/869173;
Nearest TSS
ENST00000633603/Upstream/4241; ENST00000595730/Downstream/21465;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/3566, chr19-CpG: 34/Downstream/19833
Upstream sequence
GACTTGACGAAGAGGGATCCTGTAGGGTATGAAGATGATGAGAATTAGGAAGCCGCCCTTCCTGGAGACCCTCTAAAATAGACTTACCCAAATGGAATAT
Downstream sequence
GATGACAAATTCAACATTTCCAAGGCGCTACAATAGGAGTCATTACCAGAAACCCTACAATAACAACCTCCGGGAAACCCTAGCACAGAAACCATGATGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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