Basic Information
VIS ID
TVIS44021357
Fusion event
HTLV-1-LOC105372544 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
17128634/17147989 (Hg38)
End
17128634/17147989 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105372544
Nearest miRNA
hsa-mir-103a-2/Upstream/6498294; hsa-mir-1-1/Downstream/1322626;
Nearest TSS
ENST00000382410/Upstream/283841; ENST00000470007/Downstream/78118;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/417519, chr20-CpG: 36/Downstream/77894
Nearby gene
PCSK2(+78118) ;
Upstream sequence
ATGAGAGTAGATGCATTGGCTTCCAGTCACACGCCCTGATGTTCTCCCTTTTTCCCTGATAAGCAGCAGCTCAATAAGAGATTTGCCCAAGTGTTTGTTA
Downstream sequence
TTTTGCAGCCTGACAGGGAGGCACTTTCAAAAGGTTTGCTTTCTTCTTTTGCAGGACTACTAGGCATGTAGAGAAACTCTCTAGATGCTCAGtgtattca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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